import tkinter as tk  

main_window = tk.Tk()
main_window.geometry("520x580")

def on_click(key: str):    
    print(f"Click on: {key}")
    
for i in range(4):
    main_window.grid_rowconfigure(i, weight=1, uniform="rows")  
    main_window.grid_columnconfigure(i, weight=1, uniform="cols")

columna_letras:list[str] = ['A', 'B', 'C', 'D']
tarjetas:dict[str, tk.Button] = {}
 
for fila in range(4):    
    for columna in range(1, 4+1):
        clave = f"{columna_letras[fila]}{columna}" 
        boton = tk.Button(main_window, text=clave, command=lambda k=clave:on_click(k))
        boton.grid(row=fila, column=columna-1, sticky="nsew", padx=6, pady=6)
        tarjetas[clave] = boton

main_window.mainloop()